Found 43 matching trials
To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer
N/AThis is a multi-center biomarkers study aiming to prospectively collect bio...
Location
Hospital Santo Stefano
Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases
PHASE1This is a single arm study of abemaciclib and endocrine therapy with stereo...
Location
Moffitt Cancer Center
Chemotherapy Omission in ER+/HER2- Breast Cancer With 1-3 Positive Lymph Nodes Receiving Extended Adjuvant Abemaciclib
PHASE3This is a prospective, randomized, open-label, multicenter phase III study ...
Location
Zhimin Cancer Shao
Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer
PHASE3AMBRE is a phase III study comparing two standard treatments as initial met...
Status
Active Not Recruiting
Location
Centre Hospitalier Lyon Sud
Chemo-free in Older (≥65) Node-Positive ER+/HER2- Breast Cancer
PHASE3This study is a prospective, open-label, multicenter, randomized controlled...
Location
Multiple Locations
Abemaciclib in Combination With Endocrine Therapy as First Line Therapy in Metastatic Breast Cancer Patients
N/ABreast cancer is one of the most common cancers in women. 20-30 % of all br...
Location
Klinikum rechts der Isar der TU München, Klinik und Poliklinik für Frauenheilkunde
A Study of Abemaciclib in Indian Women With Advanced Breast Cancer
PHASE4The main purpose of this study is to learn more about the safety and tolera...
Location
MNJ Institute of Oncology
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
PHASE1The main purpose of this study is to learn more about the safety, side effe...
Location
Mayo Clinic of Scottsdale
Abemaciclib for the Treatment of Luminal Metastatic breAst caNcer in the Real-life Clinical pracTice in Russia.
N/AThe ATLANT study is prospective, multicentre, non-interventional, observati...
Location
Russian Society of Clinical Oncology
Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer
PHASE3Given the uncertain benefit in efficacy of adding CDK 4/6 to first rather t...
Status
Active Not Recruiting
Location
Jeroen Bosch Ziekenhuis